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  Volume: 26
Number: 3
Term: MAY/JUN
Linked supplements:
  
CONTENTS
EDITORIAL
CONTINUOUS PROCESSING
BIOCIDES
MICROWAVES
CHIRAL TECHNOLOGIES
ORGANOMETALLIC REACTIONS
BIOFUEL
FLAVOURS
METATHESIS REACTIONS
NEWS
Cost price-driven routescouting: turning art into industrial science
Authors: BROXERTMAN R. (DSM)
The production history of most pharmaceutical ingredients - and of fine chemicals in general - starts with the identification and experimental proof-of-principle (p-o-p) of a synthesis route on laboratory scale
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Agitated continuous mini-reactors: an industrial option for Fine Chemicals
Authors: DE PANTHOU F., GIULIANO P. (AET GROUP, FRANCE)
Continuous processes for fine chemicals have been largely investigated in the past years and many types of equipments have been developed.
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Flow reactors for drug discovery. Flow for reaction optimization, library synthesis, and scale up
Authors: JONES R.V., CSAJAGI C., SZEKELYHIDI Z., KOVACS I., ET ALL (ThalesNano, HUNGARY)
The application of flow reactors as a solution to the current drug discovery compound synthesis bottleneck is explored.
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Novel process of incorporating silver biocides into polymers
Authors: SAMBHY V., SEN A. (The Pennsylvania State Univ, USA)
Surface-centred microbial infestations have been implicated in nosocomial infections, food spoilage, spread of foodborne diseases and bio fouling of materials.
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Biodeterioration-tests on wood/plastic composites
Authors: STEPHAN I., PLARRE R. (BAM Federal Inst., GERMANY)
The purpose of this article is to raise awareness about the possibilities for biodeterioration of wood/plastic composites (WPCs)
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Mizoroki-Heck reactions promoted by microwave irradiation – Part I: general aspects, reaction media and conditions
Authors: BONRATH W., LETINOIS U., NETSCHER T., SCHÜTZ J. (DSM, SWITZERLAND)
The Mizoroki-Heck reaction belongs to the group of most important palladium catalyzed C-C bond formation reactions. Microwave irradiation in synthesis allows rapid heating and efficient chemical transformation, being especially important for reactions requiring long reaction times.
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Mizoroki-Heck reactions promoted by microwave irradiation. Part II: selectivity, applications and special techniques*
Authors: BONRATH W., LETINOIS U., NETSCHER T., SCHÜTZ J. (DSM, SWITZERLAND)
This review on the microwave assisted Mizoroki-Heck reaction covers aspects of intramolecular, regio- and enantioselective transformations, as well as use of solid materials for catalyst support and binding starting materials and products.
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Frontiers in microwave process monitoring
Authors: VAUCHERS., NICULA R. (EMPA, SWITZERLAND)
Microwave processing of materials becomes increasingly interesting as low energy consumption alternative to conventional heating methods
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Chiral chemistry of single molecules
Authors: CAGLIOTI L., PÁLYI. (UNIVERSITY LA SAPIENZA, ITALY)
If a single chiral molecule stands alone in a chemical system (sample) it provides necessarily 100 percent e.e. (enantiomeric excess).
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N-Phthaloyl-L-Glutamic anhydride. A chiral Gamma-L-Glutamyl transfer reagent
Authors: KALYANAM N., MAJEED M. (Sabinsa, USA)
A readily available ã-glutamyl transfer reagent, namely, N-phthaloyl-L-glutamic anhydride (NPGLA) offers a simple solution for the racemization free synthesis of ã-glutamyl amino acids with usefully enhanced properties
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Advances in the use of organozinc halides
Authors: HAMILTON P.N., BURKHARDT E.R., MATOS K. (BASF, USA)
Organozinc halide reagents are highlighted in Negishi C-C coupling reactions and for ketone synthesis.
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PRODUCT FOCUS - CHEMSPEED TECHNOLOGIES
Authors: CHEMSPEED TECHNOLOGIES (SWITZERLAND)
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Palladium-catalysed polymerisation of polar vinyl monomers
Authors: NOZAKI K., ALBERTO A., MAGRO N. (Univ of Tokyo, JAPAN)
The introduction of polar groups into polymers is highly attractive in order to modify the polymer properties
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Modified syndiotactic polystyrenes from single-site rare-earth catalysts
Authors: EVGUENI K., JEAN-FRANÇOIS C. (Inst de Chimie de Rennes, FRANCE)
Recent progress in syndiospecific copolymerization of styrene with ethylene and/or isoprene with single-site rare-earth catalysts is presented.
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Avantium steps ahead with its Biofuels program
Authors: DE MARIA G.
Last month Chemistry Today flew to Amsterdam to meet some representatives of the company Avantium.
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Delivering scents and flavours - lessons from the pharmaceutical industry
Authors: CONWAY B.R. (Aston Univ, UK)
Active pharmaceutical ingredients (API) are most frequently administered in oral formulations which must demonstrate an acceptable degree of palatability in addition to the obvious therapeutic value
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Olefin metathesis in the pharmaceutical industry and recent development of ruthenium catalysts
Authors: PEDERSON R.L., KIBLER J. (Materia, USA)
Olefin metathesis has revolutionized the way scientists think and do chemistry
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Fine chemicals from Cardanol via Cross metathesis reaction
Authors: MELE G., LI J., VASAPOLLO G. (Univ OF Salento, ITALY)
Cardanol is a renewable and natural material, widely available, relatively low-cost obtained as by-product of the cashew industry for the edible use of cashew kernel
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