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Controlled Turbulent Mixing Improves Flow Chemistry Reproducibility To achieve highly reproducible flow chemistry scale-up

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Why validation is key to the industrialization of cell and gene therapies

A particular challenge associated with commercializing a cell and gene therapy (CGT) product is defining and performing a successful process and product validation campaign. This is particularly challenging due to limited experience, data and guidance currently available for CGT products. BioPhorum’s CGT validation workstream have published an article highlighting these issues, showcasing a number of unique validation challenges, and potential solutions, associated with CGT validation. Here we speak with one of the lead authors, Sharif Ahmed of Bayer, who kindly highlights some of these challenges, key takeaways/recommendations from the team, and the benefits of working as a cross-industry collaboration to discuss and identify potential solutions to common challenges.

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Industrial production of acetic acid: a patent landscape

This work presents an overview of the patent activity and filing trends on acetic acid industrial processes. Data were obtained with Orbit Intelligence patent database, using both keywords and classification codes (IPC, CPC, and C-sets). The complete search strategy has been reported. Data analysis reveals that methanol carbonylation is the most patented process, while fermentation methods are the most attractive technologies. The filing of new patent applications shows a decreasing trend in the period comprising 2016 and 2020 for all technologies

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Packaging pharma take care of patients and planet

Pharmapack, that still remains one of the major fairs for pharmaceutical packaging, was postponed -due to the pandemic- from February to May 2021 and finally took place in October 2021 in Paris in a face-to-face Exhibition, virtual conferences and Award Ceremony. A winning mix appearing as an opening window on innovations: let’s have an overview.

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Supporting human rights within the pharmaceutical supply chain

In the spotlight because of the Covid-19 pandemic, and with growing expectations on all companies to identify and mitigate risks in their supply chain, the pharmaceutical sector is increasingly under pressure to show that it is doing its part to respect human rights. This is however a challenging endeavor as pharmaceutical corporations rely on longer and more complex supply chains than most industries. The Pharmaceutical Supply Chain Initiative (PSCI) is committed to support our members to implement the UN Guiding Principles on Human Rights within their supply chains. With free and high-quality training materials, maturity models, and resources from the PSCI pharma companies and suppliers can identify and mitigate human rights risks and ultimately build responsible supply chains.

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