Iptacopan hydrochloride
4 March 2024
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Iptacopan (Fabhalta) was approved in December 2023 by the US Food and Drug Administration
Issue: Vol. 42
How the chemical sector is sparking a change in carbon accounting
4 March 2024
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Together for Sustainability (TfS) (1)– a global chemical industry initiative – and its 50 member companies are driving a shift in carbon accounting methodologies within the chemical industry. In its first ever White Paper (2), TfS identifies three areas for improvement: including biogenic carbon accounting, mass balance as a transitional mechanism and the use of recycled materials. These recommendations aim to incentivise the adoption of sustainable practices within the industry, and push for a recalibration of existing carbon accounting standards.
IBSA – Osteoarthritis and viscosupplementation
4 March 2024
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Today osteoarthritis constitutes the most common cause of musculoskeletal disability across the globe
Process efficiency and supply chain transparency underpin innovation, collaboration, and progress to Net Zero
4 March 2024
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Digitalisation of manufacturing operations and associated quality control have become competitive imperatives. REPHINE’s Dr. Eduard Cayón outlines how these imperatives will combine with other emerging priorities to create a roadmap through the challenges of the coming year.
Success in the gene therapy space relies on embracing technological advances in upstream and downstream processes
4 March 2024
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The gene therapy industry has witnessed a significant increase in the number of approved therapies for monogenic disorders and diseases in recent years. This growth can be attributed to the rapid advancements in the field and the use of innovative technologies and techniques aiming to improve safety and efficacy.
However, production costs remain a fundamental concern for gene therapy developers, with some treatments costing millions of dollars per dose, consequently limiting patient access.
In this article, Kai Lipinski, Ph.D., CSO at ReciBioPharm, explores the impact of trending innovation in technologies used throughout gene therapy development on improving safety, efficacy and manufacturing costs. Providing his unique insight, Kai also addresses the challenges gene therapy producers must navigate to deliver broader patient access to these revolutionary medicines.
Sustainability: exploring its significance at Angelini Pharma
4 March 2024
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WHY TO PURSUE IT Sustainability has been a frequently mentioned concept over the last
Digital innovation in doing what patients need next – Enabling speed, efficiency and culture in pharmaceutical technical development
4 March 2024
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Digital innovation is a critical enabler for advancing a molecule in the pipeline to make it into a product. Right way of capturing data by using FAIR principles is one of the key requirements to ensure seamless data flow and enable other advanced applications such as machine learning and computational modeling across the value chain. These then enable speed to patients, efficiency in operations with increased productivity and support robust design. We are also focusing on establishing the digital mindset across our organization. We have provided examples using machine learning and computational modeling taking technical development to the next level using digital innovation.
Indena’s CDMO services offer a full range of manufacturing capabilities for pharmaceutical ingredients
4 March 2024
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In a challenging CDMO framework, Indena has acquired the experience and the equipment to handle high potent NCEs and commercial products. Moreover, the company is able to ensure business continuity, thanks to 100 years of expertise and solid supply chain, its financial solidity and an ownership that has lasted for one hundred years . Two more pillars of Indena’s custom services are a continuous search for innovation, which allows the company to design science based breakthrough solutions for the clients, and its commitment to sustainability…
Navigating the chemical revolution: A roadmap for sustainable and digitally-driven manufacturing
4 March 2024
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This is a time of change for makers of chemicals; a mixture of political, economic, and ecosystem pressure is creating stresses on the way complex chemical products are made for society. News feeds provide a daily reminder of how climate change, growing resource scarcity, and supply issues are challenging and creating shortages in the supply of important products like medicines….